Agata K Kolodziej-Macczak has her expertise in wound healing and active dressings. She has worked as a Pharmacist, Master degree in Pharmacy and studying medicine as her second Faculty
Rich history of gold that goes back thousands of years and rediscovering various possibilities of use of this metal especially in some medical and pharmaceutical branches focus attention of scientists from all over the world. More and more researches over potential of Gold Nanoparticles (GNPs) in therapies of tumors are being done. Results of experiments comparing properties of different nanoparticles forms and their modifications emerge every year. Maybe it will be possible soon to create a form of gold completely safe as a medicine that could destroy illnesses towards which mankind is still largely helpless. Anyway, gold nanoparticles and some gold complex compounds may have future in oncology ahead. What is more, novel ways GNPs synthesis are being developed, especially those using plants. Some forms of gold are successfully applied in wound healing therapies and regenerative medicine as well as towards various pathogenic microorganisms. Among all kinds of gold forms, high hopes are bound especially to gold nanoparticles as they may be applied in many ways, not only as a remedy, but also used in diagnostic techniques. Gold is recognized as biocompatible material, but more research towards possible side effects is needed. This work presents information set concerning connections between gold applications in different medical fields.
Ryan Bender is currently pursuing his MD at SUNY Downstate Medical Center in Brooklyn, NY and is also working on his research at the Laboratory of Bioregenerative Medicine and Surgery at Weill Cornell Medicine in New York. He has completed his Graduation cum laude from Cornell University with a degree in Biological Engineering and a minor in Biomedical Engineering.
While tissue engineering offers the promise of revolutionary innovation, the cost of bioreactors necessary for large construct tissue culture is often prohibitive. Using our methods, several perfusion-capable tissue-culture devices were built for under 25 USD per device. These devices allowed large 3D tissue culture devices-up to 50 mm×50 mm - to be maintained in a sealed sterile environment after assembly, avoiding the problems associated with unsealed petri dishes. Our devices consisted of individual autoclavable containers with multiple access ports. Media changes were performed via peristaltic pump perfusion or with syringebased cell culture techniques through luer-lock stopcocks. Tissue constructs were live-imaged with lightmicroscopy through the window section of the device and fluorescent-protein-expressing cells were imaged with inverted fluorescence microscopy. The low cost of component parts allows rapid customization for individual experiments, including the addition of separate inlets to adjust media level in compartments of the device. Notably, these devices were maintained on perfusion culture with a pump external to the incubator for 14 days and developed no contamination. While original models of our devices used silicone and parafilm to hold the tubing in place in the lid, newer iterations seek to utilize custom-designed pieces of PDMS that will hold the tubing in place and obviate the use of adhesives for device construction. We hope to make the device even easier to assemble, with quick-locking pieces to streamline assembly.